EAATs(Glutamate transporters)
EAATs (Glutamate transporters, Excitatory amino-acid transporters,SLC1, GLT-1), being the most abundant subtype of glutamate transporter in the CNS, is a protein thatplays a key role in regulation of glutamate neurotransmission. and are sodium- and potassium-dependent members of the solute carrier family 6 (SLC1) found widely distributed throughout the brain. There are five EAAT subtypes, each with a specific primary distribution; EAAT1 (cerebellar glia), EAAT2 (forebrain glia), EAAT3 (cortical neurons), EAAT4 (cerebellar Purkinje neurons) and EAAT5 (retina).
-
CP 154526是选择性非肽类 CRF1 拮抗剂。
More
-
Ceftriaxone disodium salt是神经保护活性， 加强EAAT2 的表达和活性。
More
-
Antalarmin hydrochloride是CRF1 拮抗剂。
More
-
(±)-threo-3-Methylglutamic acid是EAAT2，EAAT4 blocker (EAAT2，EAAT4阻断剂)。
More
-
(±)-HIP-A是活性的， 非竞争性 EAAT 抑制剂。
More
